You are on page 1of 5

IAJPS 2017, 4 (08), 2223-2227 Asra Jabeen et al ISSN 2349-7750

CODEN [USA]: IAJPBB ISSN: 2349-7750

INDO AMERICAN JOURNAL OF

PHARMACEU TICAL SCIENCES

Available online at: http://www.iajps.com Review Article

A REVIEW ON LEPIDIUM SATIVUM


Asra Jabeen*1, Dr. S. Rani2, Dr. Mohammed Ibrahim3, Abdul Saleem Mohammad4,
1
Associate Professor, Department of Pharmacognosy, Nizam Institute of Pharmacy, Deshmukhi
(V), Pochampally (M), Behind Mount Opera, Yadadri Bhuvanagiri (Dist)-508284,
Telangana, India.
2
Assistant Professor, Annamalai University, Sadagopan Nagar, Annamalai Nagar, Chidambaram,
Tamil Nadu 608002, India.
3
Professor and Principal, Prathap Narender Reddy College of Pharmacy, Peddashapur,509325,
Shamshabad, Telangana, India.
4
Assistant Professor, Department of Pharmaceutical Analysis and Quality Assurance, Nizam
Institute of Pharmacy, Deshmukhi (V), Pochampally (M), Behind Mount Opera, Yadadri
Bhuvanagiri (Dist)-508284, Telangana, India.

Abstract:
Lepidium sativum plant and seeds are considered one of the popular medicinal herbs used in the community of Saudi
Arabia, Sudan and some other Arabic countries as a good mediator for bone fracture healing in the human skeleton. A
number of recent studies pointed out the traditional uses of Lepidium sativum seeds extract in controlling many clinical
problems. They were used as anti-asthmatic antiscorbutic, aperient, diuretic, galactogogue, poultice and stimulant. The
traditional plants may represent new sources of drugs with stable, biologically active components that can establish a
scientific base for the use of plants in modern medicine. These local ethnomedical preparations and prescriptions of
plant sources should be scientifically evaluated and then disseminated properly.
Key Words: Seeds, garden cress, hydroponic, phytochemicals, nutritional.
Corresponding Author:
Asra Jabeen, QR code
Associate Professor,
Department of Pharmacognosy,
Nizam Institute of Pharmacy, Deshmukhi (V), Pochampally (M),
Behind Mount Opera, Yadadri Bhuvanagiri (Dist)-508284,
Telangana, India.
Phone number: - 9700889601
E-mail address: - asra_pharma@yahoo.com

Please cite this article in press as Asra Jabeen et al, A Review on Lepidium Sativum,Indo Am. J. P. Sci, 2017; 4(8).

www.iajps.com Page 2223


IAJPS 2017, 4 (08), 2223-2227 Asra Jabeen et al ISSN 2349-7750

INTRODUCTION:[1-9] Edible shoots are typically harvested in one to two


Cress (Lepidium sativum), sometimes referred to as weeks after planting, when they are 5–13 cm (2–5 in)
garden cress to distinguish it from similar plants also tall. Garden cress is added to soups, sandwiches and
referred to as cress (from old Germanic cresso which salads for its tangy flavor. It is also eaten as sprouts,
means sharp, spicy), is a rather fast-growing, edible and the fresh or dried seed pods can be used as a
herb. Garden cress is genetically related to watercress peppery seasoning (haloon). In the United Kingdom,
and mustard, sharing their peppery, tangy flavor and cut cress shoots are commonly used in sandwiches with
aroma. In some regions, garden cress is known as boiled eggs, mayonnaise and salt.Raw cress is 89%
mustard and cress, garden pepper cress, pepperwort, water, 6% carbohydrates (including 1% dietary fiber),
pepper grass, or poor man's pepper. This annual plant 3% protein and less than 1% fat (table). In a 100 gram
can reach a height of 60 cm (~24 inches), with many amount, raw cress supplies 32 calories and numerous
branches on the upper part. The white to pinkish nutrients in significant content, including vitamin K
flowers are only 2 mm (1/12 of an inch) across, (516% of the Daily Value, DV), vitamin C (83% DV)
clustered in branched racemes. When consumed raw, and vitamin A (43% DV). Among dietary minerals,
cress is a high-nutrient food containing substantial manganese levels are high (26% DV) while several
content of vitamins A, C and K and several dietary others, including potassium and magnesium, are in
minerals. moderate contentGarden cress, known as
chandrashoor, and the seeds, known as aleev in
Marathi, or halloo in India, are commonly used in the
system of Ayurveda.
Garden cress is ideally grown hydroponically whereby
the cress is cultivated without soil using mineral
nutrient solutions in water. Garden cress is usually
harvested within two weeks of cultivation and can be
preserved by placing the stems in a water container and
then refrigerating them for at least one week
History [10-12]
It is considered to have originated from Persia and later
spread to the gardens of India, Syria, Greece and
Egypt. Garden cress is still popular and frequently
consumed type of leafy vegetables in Europe,
Fig1: Garden cress is commercially grown in especially in Scandinavia, Netherlands, England and
England, France, the Netherlands and Scandinavia. France (centers of the garden cress cultivation) where it
Cultivation of garden cress is practical both on mass is grown commercially. Due to its delightful and
scales and on the individual scale. Garden cress is peppery taste it is grown all over the world and is used
suitable for hydroponic cultivation and thrives in as healthy addition to salads and sandwiches.
slightly alkaline water. In many local markets, the Scientific classification:
demand for hydroponically grown cress can exceed Kingdom: Plantae (Plants)
available supply, partially because cress leaves are not Subkingdom: Tracheobionta (Vascular plants)
suitable for distribution in dried form, so they can only Superdivision: Spermatophyta (Seed plants)
be partially preserved. Consumers commonly acquire Division: Magnoliophyta (Flowering
cress as seeds or (in Europe) from markets as boxes of plants)
young live shoots. Class: Magnoliopsida (Dicotyledons)
Subclass: Dilleniidae
Order: Capparales
Family: Brassicaceae/Cruciferae (Mustard
family)
Genus: Lepidium L. (Pepperweed)
Species: Lepidium sativum L.
(Gardencress pepperweed)

Chemical Constituents [13-15]


The seeds shows the presence of carbohydrates,
phenolic compounds, flavonoids, alkaloids, proteins,
saponins and lipids. Thirty four percent of the total
Fig 2: Seeds of Lepidium sativum

www.iajps.com Page 2224


IAJPS 2017, 4 (08), 2223-2227 Asra Jabeen et al ISSN 2349-7750

fatty acids are alpha linolenic acid; and the oil has 10. Milk Production
alpha linoleic acid which could give it nutritional Consuming garden cress helps to stimulate the
advantages (Diwakara et al., 2008). The primary fatty mammary glands to start producing milk in lactating
acids in Lepidium sativum oil were oleic and linolenic mothers. Due to this powerful property of garden cress,
acids and was found to contain high concentrations of new mothers are encouraged to eat food containing
tocopherols. It contains good amount of lignans and garden cress to facilitate milk production. Moreover,
antioxidants, which can stabilize the n-3 due to the high protein and iron contents of garden
polyunsaturated fatty acids in its seed oil. The primary cress, it is ideally given post-partum to breastfeeding
phytosterols in Lepidium sativum were sitosterol and mothers.
campesterol, with avenasterol. The plant is known to 11. Aphrodisiac
contain imidazole, lepidine, semilepidinoside A and Consumption of garden cress greatly helps to improve
B, β-carotenes, ascorbic acid, linoleic acid, oleic acid, and boost libido.
palmitic acid, stearic acid, sinapic acid and sinapin. 12. Gastrointestinal Treatment
Benefits of Garden Cress [16-21] Garden cress can be used as a laxative and purgative
1. Medicinal Properties for patients suffering from constipation. Garden cress
Both the leaves, stems and seeds of garden cress are seeds can be blended and mixed with honey, which is
used in preparing traditional medicine for example; the used for treating diarrhoea and dysentery. Garden cress
seed are used as remedy for minimizing asthma can be blended and infused with hot water, which is
symptoms as well as improves lung function in people used for treating colic especially in children.
suffering from asthma. Also garden cress can be used 13. Anti-carcinogenic
for treating patients suffering from bleeding piles. Garden cress seeds have antioxidants that help to
2. Menstrual Cycle Regulation prevent free radicals from damaging the body cells.
The garden cress seeds contain phytochemicals that are Due to this property, it can serve as a chemoprotective
similar to estrogen therefore consuming them helps to drugs for protecting the body from cancerous growths.
make irregular menstruation become more regular. 14. Nutritional Values of Garden Cress
3. Indigestion Garden cress is an excellent source of folic acid,
Garden cress seeds can be eaten to relieve the vitamins C, dietary fiber, iron, calcium, protein,
symptoms of constipation and indigestion. vitamin A, folate and vitamin E. The seeds of garden
4. Respiratory Infection Treatment cress are also highly nutritive and they contain ascorbic
Garden cress seeds can be chewed or blended and acid, tocopherol, folic acid, calcium, linoleic fatty
mixed with honey, which is taken as an expectorant for acids, iron, beta-carotene and arachidic.
treating cold, headache, asthma, sore throat and cough.
5. Iron Deficiency Treatment 15. Memory Booster
Garden cress seeds are used for treating patients Garden cress seeds contain arachidic fatty acid and
suffering from iron deficiency anemia. Consumption of linoleic acids thus can serve as a memory booster.
these seeds help to boost the haemoglobin level over Side-effects of Garden Cress [22-31]
time. 1. Diuretic Properties
6. Culinary Purposes Garden cress contains diuretic properties thus patients
Garden cress is characterised by peppery, aromatic and suffering from frequent passage of water and urine
tangy flavour. It can be eaten raw in salads and should be cautious when using this plant.
sandwiches or used as herbs for food seasoning. The 2. Abortifacient Properties
seeds can also be roasted with salt before eating. Garden cress is abortifacient in nature thus capable of
7. Dermatological Treatment inducing abortion in early pregnant women if taken in
Garden cress seeds can be blended with water and excess. Pregnant women should refrain from eating
honey to form a thick paste that can be applied on garden cress as it has the tendency to induce uterine
the skin to treat sunburn, irritated skins, dry skin and contractions and abortion. Garden cress seeds can
broken lips. increase uterine contraction, thus certain people use it
8. Hair Loss Treatment to induce labor in late stages of pregnancy.
Garden cress is an excellent source of protein and iron 3. Goitrogenic Properties
thus can be used for treating people suffering from hair Garden cress contains goitrogens, which are substances
loss. that subdue the proper functioning of the thyroid gland
9. Immunity Boost through its interference with iodine absorption. If
Consumption of both garden cress stems, leaves and consumed in large quantities can cause the thyroid
seeds help to boost the immune system. gland to enlarge, thereby causing goiter and
hypothyroidism.

www.iajps.com Page 2225


IAJPS 2017, 4 (08), 2223-2227 Asra Jabeen et al ISSN 2349-7750

FACTS ON MEDICINAL VALUES: [32-39] regions of Saudi Arabia, such as Hijaz, AL-Qaseem,
Lepidium sativum in general is Antiasthmatic in nature; and the Eastern Province. In Europe and America, the
therefore, it provides natural breathing during Asthma leaves are used in salad. In various countries of
and cures it. It has the ability to improve the appetite in Africa, Lepidium sativum seeds are thought to be an
Anorexia patient. It effectively expels tapeworms from effective medicinal remedy to cure respiratory
the body. It advantageously inhibits the oxidation. It disorders, like bronchitis and asthma. The plant is
provides relief from Hiccups. It protects the body from cultivated as culinary vegetable all over Asia. In South
Skin diseases. It is Stimulant in nature which increases Asia, it is used in traditional medicine to treat asthma,
the stamina. It also stimulates the body and brain bronchitis, and cough and is considered useful as
functions. Thus, it is used to treat Brain Disorders. The abortifacient, antibacterial, aphrodisiac, diuretic,
seeds are optimal to counter Gout. It treats Diarrhea. It expectorant, gastrointestinal stimulant,
has Analgesic properties which potentially relieves gastroprotective, laxative, and stomachic
from pain. It mitigates cough. Lepidium sativum has The plant is known to contain imidazole, lepidine,
Antibacterial attribute which protects the body from semilepidinoside A and B, β-carotenes, ascorbic acid,
bacterial infection. The Antidiabetic attribute is linoleic acid, oleic acid, palmitic acid, stearic acid,
essential to lower the blood sugar levels and to cure sinapic acid and sinapin. Lepidium sativum is reported
Diabetes. It heals the inflamed area of the body and to exhibit antihypertensive, diuretic, anti-inflammatory,
inhibits the inflammation. Due to Antihypertensive analgesic, anticoagulant, antirheumatic, hypoglycemic,
property, it is prescribed to treat high blood pressure. It laxative, prokinetic, antidiarrheal, and antispasmodic
is widely used to cure the symptoms of Scurvy. It is properties. It has been shown to possess antiasthmatic
considered as an effective remedy to cure Constipation. and bronchodilatory potential in preliminary studies,
It has Diuretic action which flushes out the toxins from but there is no report available in the literature on the
the body. It effectively purifies and removes the pharmacological basis for its medicinal use. Traditional
impurities from the blood. It avoids the risk of sources of medicinal plants can be extended for future
abdominal diseases. Lepidium Sativum removes bad investigation into the field of pharmacology,
breath of the mouth. The digestive effect of this herb in phytochemistry, ethnobotany and other biological
the body keeps Digestive Disorders at bay. It has the actions for drug discovery.
ability to increase the flow of urine and expelling the REFERENCES:
toxins, salt and water from the body. Thus, it hinders 1. Al-Jenoobi F. I., Al-Thukair A. A., Alam M. A., Abbas
Urinary problems. The Emmenagogue attribute F. A., Al-Mohizea A. M., Alkharfy K. M. and Saleh A.
stimulates and normalize the menstruation flow to Al-Suwayeh (2014), Effect of Garden Cress Seeds Powder
prevent menstrual disorders. Often, it is food remedy to and Its Alcoholic Extract on the Metabolic Activity of
stop Heavy Menstrual bleeding. It boosts up the CYP2D6 and CYP3A4, Evidence-Based Complementary
Immune System and protects the body from getting and Alternative Medicine.
sick. It is Hepatoprotective in nature, which prevents 2. Bedassa T., Andargie M. and Eshete M., Genetic
Liver damage. It improves the liver function and avoids divergence analysis of garden cress (Lepidium sativum L.)
International Journal of Biodiversity and
the risk of liver diseases. It relieves from the
Conservation,2013;5(11):770-771.
inflammation of the joints and treats Arthritis. It is 3. Datta P. K., Diwakar B. K., Viswanatha S., Murthy K.
potent to reduce the weight and provides relief from N. and Naidu K. A, Safety evaluation studies on Garden
Obesity. The Galactagogue effect of this herb within cress (Lepidium sativum L.) seeds in Wistar rats,
the body promotes the milk follow after pregnancy. International Journal of Applied Research in Natural
Thus, it prevents from the experience of breast milk Products,2011; 4(1).
insufficiency. The seeds are effective in fixing the 4. Diwakar B. T., Dutta P. K., Lokesh B. R., and Naidu K.
fractures and repairing the bones. The herb also has an A, Bio-availability and metabolism of n-3 fatty acids rich
Ophthalmic attribute. This makes it a good cure for garden cress (Lepidium sativum) seed oil in albino rats.
curing eye diseases. It easily reduces Blemishes of the Prostaglandins Leukot.Essent.Fatty Acids, 2008;78(2):
skin. It completely removes and reduces dandruff. The 123-125.
leaves of Lepidium sativum work as an Antidote 5.Eddouks M., Maghrani M, Effect of Lepidium sativum
against snake bite. L. on renal glucose reabsorption and urinary TGF-beta 1
levels in diabetic rats,2008; 22(1):1-3.
SUMMARY AND CONCLUSION: 6. Ketchen EE, Porter WE, Bolton NE. The biological
Lepidium sativum Linn. belongs to family Cruciferae effects of magnetic fields on man. Am Ind Hyg Assoc J.
(cabbage family) and is commonly known as 1978;39:1
“Common cress,” “Garden cress,” or “Halim.” The 7. Cook SD, Barrack RL, Santman M, Patron LP, Salkeld
plant is called “Hab el Rashaad” or “Thufa” in Saudi SL, Whitecloud TS. The Otto Aufranc Award. Strut
allograft healing to the femur with recombinant human
Arabia and is a popular herbal plant grown in many

www.iajps.com Page 2226


IAJPS 2017, 4 (08), 2223-2227 Asra Jabeen et al ISSN 2349-7750

osteogenic protein-1. Clin Orthop Relat Res. 24. Iori R, Rollin P, Streicher H, Thiem J, Palmieri S. The
2000;381:47–57. myrosinase-glucosinolate interaction mechanism studied
8. Ripamonti U. Bone induction by recombinant human using some synthetic competitive inhibitors. FEBS Lett.
osteogenic protein-1 (hOP-1, BMP-7) in the primate 1996;385:87–90.
Papio ursinus with expression of mRNA of gene products 25. Giussani A, Heinrichs U, Roth P, Werner E, Schramel
of the TGF-beta superfamily. J Cell Mol Med. P, Wendler I. Biokinetic studies in humans with stable
2005;9:911–928. isotopes as tracers. Part 1: a methodology for
9. Han ZB, Chen LP, Yang XZ. Experimental study of incorporation of trace metals into vegetables. Isotopes
fracture healing promotion with mechanical vibration in Environ Health Stud. 1998;34:291–296.
rabbits [in Chinese] Chung Hua Wai Ko Tsa Chih. 26. Patel MM, Chauhan GM, Patel LD. Mucilages of
1994;32:215–216. Lepidium Sativum, Linn (Asario) and Ocimum Canum
10. Diebert MC, McLeod BR, Smith SD, Liboff AR. Ion Sims (Bavchi) as emulgents. Indian J Hosp Pharm.
resonance electromagnetic field stimulation of fracture 1987;24:200–202.
healing in rabbits with a fibular osteotomy. J Orthop Res. 27. Wendt L, Meler J. Rheological study of
1994;12:878–885. pharmaceutical emulsions containing mucilage from the
11. Bruce GK, Howlett CR, Huckstep RL. Effect of a seeds of garden Cress instead of gum arabic. Farm Pol
static magnetic field on fracture healing in a rabbit radius (Farmacja-Polska) 1988;44:87–91.
preliminary result. Clin Orthop Related Res. 28. Pollak D, Floman Y, Simkin A, Avinezer A, Freund
1987;222:300–305. HR. The effect of protein malnutrition and nutritional
12. Ageel AM, Tariq M, Mossa JS, Al-Yahya MA, Al- support on the mechanical properties of fracture healing in
Said MS. Plants Used in Saudi Folk Medicine. Riyadh, the injuried rat. J Parenter Enteral Nutr. 1986;10:564–567.
Saudi Arabia: KACST, King Saud University Press; 1987. 29. Delgado Martinez AD, Martinez ME, Carrascal MT,
245–415. Rodriguez Avial M, Munuera L. Effect of 25-OH vitamin
13. Qudamah A. Dictionary of Food and Treatment by D on fracture healing in elderly rats. J Orthop Res.
Plants. Beirut: Dar Alnafaes; 1995. pp. 241–244. 1998;16:650–653.
14. Czimber G, Szabo LG. Therapeutical effect and 30. Lindgren JU, DeLuca HF, Mazess RB. Effects of 1, 25
production of garden cress (Lepidium Sativum L) (OH) 2D3 on bone tissue in the rabbit: studies on fracture
Gyogyszereszet. 1988;32:79–81. healing, disuse osteoporosis and prednisolone
15. Ahsan SK, Tariq M, Ageel M, Al-Yahya MA, Shah osteoporosis. Calcif Tissue Int. 1984;36:591–595.
AH. Studies on some herbal drugs used in fracture 31. The Plant List: A Working List of All Plant Species,
healing. Int J Crude Drug Res. 1989;27:235–239. retrieved 8 May 2016
16. Ricciardi L, Perissinotto A, Dabala M. Mechanical 32. Cassidy, Frederic Gomes and Hall, Joan Houston.
monitoring of fracture healing using ultrasound imaging. Dictionary of American regional English, Harvard
Clin Orthop. 1993; 293:71–76. University Press, 2002. Page 97. ISBN 0-674-00884-7,
17. Cunningham JL, Kenwright J, Kershaw CJ. ISBN 978-0-674-00884-7
Biomechanical measurement of fracture healing. J Med 33. Staub, Jack E, Buchert, Ellen. 75 Exceptional Herbs
Eng Technol. 1990;14:92–101. for Your Garden Published by Gibbs Smith, 2008. ISBN
18. Muir P, Markel MD, Bogdanske JJ, Johnson KA. Dual 1-4236-0251-X, 9781423602514
energy X-ray absorptiometry and force-plate analysis of 34. Vegetables of Canada. Published by NRC Research
gait in dogs with healed femora after leg lengthening plate Press. ISBN 0-660-19503-8, ISBN 978-0-660-19503-2
fixation. Vet Surg. 1995;24:15–24. 35. Boswell, John T. and Sowerby, James. English
19. Hulth A. Current concepts of fracture healing. Clin Botany: Or, Coloured Figures of British Plants. Robert
Orthop Related Res. 1989;249:265–284. Hardwicke, 1863. Page 215.
20. Pennig D. The biology of bones and of bone fracture 36. Vegetables of Canada. NRC Research Press. ISBN 0-
healing. Unfallchirurg. 1990;93:488–491. 660-19503-8, ISBN 978-0-660-19503-2
21. Kolodziejski J, Mruk-Luczkiewicz A, Mionskowski 37. Hirsch, David P.. The Moosewood Restaurant kitchen
H. Physiochemical investigations on the oil from seeds of garden: creative gardening for the adventurous cook. Ten
genus Lepidium L. Cruciferae. Diss Pharm Pharmacol. Speed Press, 2005. ISBN 1-58008-666-7, ISBN 978-1-
1969;21:235–239. 58008-666-0
22. Burghardt H, Brunner H, Oelmuller R, Lottspeich F, 38.http://www.organicindia.com/PR_OH_chandrashoor.p
Oster U, Rudiger W. Natural inhibitors of germination and hp
growth, VII synthesis of Ribulosebisphosphate 39. The Wealth of Indian Raw Materials,. New Delhi:
carboxylase in darkness and its inhibition by Coumarin. Z Publication and information Directorate. 1979. pp. CSIR
Naturforsch [C] 1994;49:321–326. Vol 9, Page 71–72.
23. Koropp K, Volkmann D. Monoclonal antibody CRA
against a fraction of action from Cress roots recognized its
antigen in different plant species. Eur J Cell Biol.
1994;64:153–162.

www.iajps.com Page 2227

You might also like